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Synthesis of a deuterated probe for the confocal Raman microscopy imaging of squalenoyl nanomedicines
The synthesis of ω-di-(trideuteromethyl)-trisnorsqualenic acid has been achieved from natural squalene. The synthesis features the use of a Shapiro reaction of acetone-d(6) trisylhydrazone as a key step to implement the terminal isopropylidene-d(6) moiety. The obtained squalenic acid-d(6) has been c...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979966/ https://www.ncbi.nlm.nih.gov/pubmed/27559365 http://dx.doi.org/10.3762/bjoc.12.109 |