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Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

CELADEN was a randomized placebo-controlled trial of 50 patients with confirmed dengue fever to evaluate the efficacy and safety of celgosivir (A study registered at ClinicalTrials.gov, number NCT01619969). Celgosivir was given as a 400 mg loading dose and 200 mg bid (twice a day) over 5 days. Repli...

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Detalles Bibliográficos
Autores principales: Sung, Cynthia, Wei, Yuan, Watanabe, Satoru, Lee, How Sung, Khoo, Yok Moi, Fan, Lu, Rathore, Abhay P. S., Chan, Kitti Wing-Ki, Choy, Milly M., Kamaraj, Uma S., Sessions, October M., Aw, Pauline, de Sessions, Paola F., Lee, Bernett, Connolly, John E., Hibberd, Martin L., Vijaykrishna, Dhanasekaran, Wijaya, Limin, Ooi, Eng Eong, Low, Jenny Guek-Hong, Vasudevan, Subhash G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980036/
https://www.ncbi.nlm.nih.gov/pubmed/27509020
http://dx.doi.org/10.1371/journal.pntd.0004851