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PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina

Current gene therapies predominantly use small, strong, and readily available ubiquitous promoters. However, as the field matures, the availability of small, cell-specific promoters would be greatly beneficial. Here we design seven small promoters from the human paired box 6 (PAX6) gene and test the...

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Detalles Bibliográficos
Autores principales:	Hickmott, Jack W, Chen, Chih-yu, Arenillas, David J, Korecki, Andrea J, Lam, Siu Ling, Molday, Laurie L, Bonaguro, Russell J, Zhou, Michelle, Chou, Alice Y, Mathelier, Anthony, Boye, Sanford L, Hauswirth, William W, Molday, Robert S, Wasserman, Wyeth W, Simpson, Elizabeth M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980111/ https://www.ncbi.nlm.nih.gov/pubmed/27556059 http://dx.doi.org/10.1038/mtm.2016.51

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