PTEN regulates EG5 to control spindle architecture and chromosome congression during mitosis

Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome segregation to ensure mitotic fidelity. Tumour suppressor PTEN has multiple functions in maintaining genome stability. Here we report an essential role of PTEN in mitosis through r...

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Detalles Bibliográficos
Autores principales: He, Jinxue, Zhang, Zhong, Ouyang, Meng, Yang, Fan, Hao, Hongbo, Lamb, Kristy L., Yang, Jingyi, Yin, Yuxin, Shen, Wen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980451/
https://www.ncbi.nlm.nih.gov/pubmed/27492783
http://dx.doi.org/10.1038/ncomms12355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980451/
https://www.ncbi.nlm.nih.gov/pubmed/27492783
http://dx.doi.org/10.1038/ncomms12355

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