Cargando…

Thrombopoietin receptor is required for the oncogenic function of CALR mutants

Detalles Bibliográficos
Autores principales:	Nivarthi, H, Chen, D, Cleary, C, Kubesova, B, Jäger, R, Bogner, E, Marty, C, Pecquet, C, Vainchenker, W, Constantinescu, S N, Kralovics, R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Letter to the Editor
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980558/ https://www.ncbi.nlm.nih.gov/pubmed/26883579 http://dx.doi.org/10.1038/leu.2016.32

Ejemplares similares

Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation
por: Papadopoulos, Nicolas, et al.
Publicado: (2023)

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers
por: Defour, Jean-Philippe, et al.
Publicado: (2023)

Allelic imbalance in CALR somatic mutagenesis
por: Harutyunyan, A S, et al.
Publicado: (2015)

The Thrombopoietin Receptor: Structural Basis of Traffic and Activation by Ligand, Mutations, Agonists, and Mutated Calreticulin
por: Varghese, Leila N., et al.
Publicado: (2017)

Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis
por: Plo, Isabelle, et al.
Publicado: (2017)

Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish
por: Lim, K-H, et al.
Publicado: (2016)

Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers
por: Venkatesan, Arunkumar, et al.
Publicado: (2021)

Sequential evaluation of CALR mutant burden in patients with myeloproliferative neoplasms
por: Cavalloni, Chiara, et al.
Publicado: (2017)

Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response
por: Barbieri, Daniela, et al.
Publicado: (2018)

CALR mutations in myeloproliferative neoplasms: An unfolding story
por: Langabeer, Stephen E.
Publicado: (2020)

Differential clinical effects of different mutation subtypes in CALR-mutant myeloproliferative neoplasms
por: Pietra, D, et al.
Publicado: (2016)

Effects of CALR-Mutant Type and Burden on the Phenotype of Myeloproliferative Neoplasms
por: Kim, Hyun-Young, et al.
Publicado: (2022)

Thrombopoietin levels in Quebec platelet disorder—Implications for the mechanism of thrombocytopenia
por: Hayward, C. P. M., et al.
Publicado: (2018)

Leukocytosis and presence of CALR mutation is associated with non-hepatosplenic extramedullary hematopoiesis in primary myelofibrosis
por: Barraco, D, et al.
Publicado: (2016)

Concurrent chronic myeloid leukemia and CALR-mutated myeloproliferative neoplasm
por: Langabeer, Stephen E.
Publicado: (2020)

Extracellular Domain N-Glycosylation Controls Human Thrombopoietin Receptor Cell Surface Levels
por: Albu, Roxana I., et al.
Publicado: (2011)

In and out: Traffic and dynamics of thrombopoietin receptor
por: Roy, Anita, et al.
Publicado: (2021)

Secreted mutant calreticulins as rogue cytokines in myeloproliferative neoplasms
por: Pecquet, Christian, et al.
Publicado: (2023)

Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment
por: Kjær, Lasse, et al.
Publicado: (2016)

CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia
por: Cui, Yajuan, et al.
Publicado: (2014)

Myeloproliferative neoplasm-driving Calr frameshift promotes the development of pulmonary hypertension in mice
por: Minakawa, Keiji, et al.
Publicado: (2021)

Mice with Calr mutations homologous to human CALR mutations only exhibit mild thrombocytosis
por: Shide, Kotaro, et al.
Publicado: (2019)

High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells
por: Jia, Ruochen, et al.
Publicado: (2021)

MARIMO cells harbor a CALR mutation but are not dependent on JAK2/STAT5 signaling
por: Kollmann, K, et al.
Publicado: (2015)

Dominance of an UBA1 mutant clone over a CALR mutant clone: from essential thrombocytemia to VEXAS
por: Hage-Sleiman, Mehdi, et al.
Publicado: (2021)

Thrombopoietin and its receptor in normal and neoplastic hematopoiesis
por: Kaushansky, Kenneth
Publicado: (2016)

Thrombopoietin receptor agonists: ten years later
por: Ghanima, Waleed, et al.
Publicado: (2019)

Effect of Thrombopoietin Receptor Agonist on Pregnant Mice
por: Nakai, Kensaku, et al.
Publicado: (2022)

Role of Thrombopoietin Receptor Agonists in Inherited Thrombocytopenia
por: Bastida, José María, et al.
Publicado: (2021)

The Thrombopoietin Receptor, MPL, Is a Therapeutic Target of Opportunity in the MPN
por: Spivak, Jerry L., et al.
Publicado: (2021)

Frequent CALR exon 9 alterations in JAK2 V617F-mutated essential thrombocythemia detected by high-resolution melting analysis
por: Lim, K-H, et al.
Publicado: (2015)

Differences in Hematological and Clinical Features Between Essential Thrombocythemia Cases With JAK2- or CALR-Mutations
por: Kubuki, Yoko, et al.
Publicado: (2017)

Use of Thrombopoietin Receptor Agonists in Childhood Immune Thrombocytopenia
por: Garzon, Angelica Maria, et al.
Publicado: (2015)

Optimal use of thrombopoietin receptor agonists in immune thrombocytopenia
por: Al-Samkari, Hanny, et al.
Publicado: (2019)

Thrombocytopenia and Procedural Prophylaxis in the Era of Thrombopoietin Receptor Agonists
por: Nilles, Kathy M., et al.
Publicado: (2019)

The thrombopoietin receptor: revisiting the master regulator of platelet production
por: Hitchcock, Ian S., et al.
Publicado: (2021)

CALR mutation characterization in myeloproliferative neoplasms
por: Bilbao-Sieyro, Cristina, et al.
Publicado: (2016)

CALR Mutation Underlying Silent Stroke
por: Faryal, Rehman, et al.
Publicado: (2021)

Switching thrombopoietin receptor agonist treatments in patients with primary immune thrombocytopenia
por: González-Porras, José R., et al.
Publicado: (2019)

Endocytosis of the thrombopoietin receptor Mpl regulates megakaryocyte and erythroid maturation in mice
por: Eaton, Nathan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bsnfpkjf0rfpilf81sbra6jha0