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A virtual lymph node model to dissect the requirements for T-cell activation by synapses and kinapses
The initiation of T-cell responses in lymph nodes requires T cells to integrate signals delivered by dendritic cells (DCs) during long-lasting contacts (synapses) or more transient interactions (kinapses). However, it remains extremely challenging to understand how a specific sequence of contacts es...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980574/ https://www.ncbi.nlm.nih.gov/pubmed/27089942 http://dx.doi.org/10.1038/icb.2016.36 |