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Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA
The development of a ligand that is capable of distinguishing among the wide variety of G-quadruplex structures and targeting telomeres to treat cancer is particularly challenging. In this study, the ability of two anthraquinone telomerase inhibitors (NSC749235 and NSC764638) to target telomeric G-q...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980623/ https://www.ncbi.nlm.nih.gov/pubmed/27511133 http://dx.doi.org/10.1038/srep31019 |