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Natural product derivative BIO promotes recovery after myocardial infarction via unique modulation of the cardiac microenvironment

The cardiac microenvironment includes cardiomyocytes, fibroblasts and macrophages, which regulate remodeling after myocardial infarction (MI). Targeting this microenvironment is a novel therapeutic approach for MI. We found that the natural compound derivative, BIO ((2′Z,3′E)-6-Bromoindirubin-3′-oxi...

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Detalles Bibliográficos
Autores principales:	Kim, Yong Sook, Jeong, Hye-yun, Kim, Ah Ra, Kim, Woong-Hee, Cho, Haaglim, Um, JungIn, Seo, Youngha, Kang, Wan Seok, Jin, Suk-Won, Kim, Min Chul, Kim, Yong-Chul, Jung, Da-Woon, Williams, Darren R., Ahn, Youngkeun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980696/ https://www.ncbi.nlm.nih.gov/pubmed/27510556 http://dx.doi.org/10.1038/srep30726

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