DL-ADR: a novel deep learning model for classifying genomic variants into adverse drug reactions

BACKGROUND: Genomic variations are associated with the metabolism and the occurrence of adverse reactions of many therapeutic agents. The polymorphisms on over 2000 locations of cytochrome P450 enzymes (CYP) due to many factors such as ethnicity, mutations, and inheritance attribute to the diversity...

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Detalles Bibliográficos
Autores principales: Liang, Zhaohui, Huang, Jimmy Xiangji, Zeng, Xing, Zhang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980789/
https://www.ncbi.nlm.nih.gov/pubmed/27510822
http://dx.doi.org/10.1186/s12920-016-0207-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980789/
https://www.ncbi.nlm.nih.gov/pubmed/27510822
http://dx.doi.org/10.1186/s12920-016-0207-4

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