Cargando…
Ubiquitin C-terminal hydrolase L1 (UCH-L1): structure, distribution and roles in brain function and dysfunction
Ubiquitin C-terminal hydrolase L1 (UCH-L1) is an extremely abundant protein in the brain where, remarkably, it is estimated to make up 1–5% of total neuronal protein. Although it comprises only 223 amino acids it has one of the most complicated 3D knotted structures yet discovered. Beyond its expres...
Autores principales: | Bishop, Paul, Rocca, Dan, Henley, Jeremy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980807/ https://www.ncbi.nlm.nih.gov/pubmed/27515257 http://dx.doi.org/10.1042/BCJ20160082 |
Ejemplares similares
-
The Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) C Terminus Plays a Key Role in Protein Stability, but Its Farnesylation Is Not Required for Membrane Association in Primary Neurons
por: Bishop, Paul, et al.
Publicado: (2014) -
Ubiquitin C-Terminal Hydrolase-L1 (UCH-L1) in Prediction of Computed Tomography Findings in Traumatic Brain Injury; a Meta-Analysis
por: Ramezani, Fatemeh, et al.
Publicado: (2018) -
Ubiquitin Carboxy-Terminal Hydrolase L1 (UCH-L1) is increased in cerebrospinal fluid and plasma of patients after epileptic seizure
por: Mondello, Stefania, et al.
Publicado: (2012) -
Ubiquitin Carboxyl-Terminal Hydrolases (UCHs): Potential Mediators for Cancer and Neurodegeneration
por: Sharma, Amit, et al.
Publicado: (2020) -
Ubiquitin C-Terminal Hydrolase L1 in Tumorigenesis
por: Hurst-Kennedy, Jennifer, et al.
Publicado: (2012)