The relationship between endogenous thymidine concentrations and [(18)F]FLT uptake in a range of preclinical tumour models

BACKGROUND: Recent studies have shown that 3′-deoxy-3′-[(18)F] fluorothymidine ([(18)F]FLT)) uptake depends on endogenous tumour thymidine concentration. The purpose of this study was to investigate tumour thymidine concentrations and whether they correlated with [(18)F]FLT uptake across a broad spe...

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Detalles Bibliográficos
Autores principales: Heinzmann, Kathrin, Honess, Davina Jean, Lewis, David Yestin, Smith, Donna-Michelle, Cawthorne, Christopher, Keen, Heather, Heskamp, Sandra, Schelhaas, Sonja, Witney, Timothy Howard, Soloviev, Dmitry, Williams, Kaye Janine, Jacobs, Andreas Hans, Aboagye, Eric Ofori, Griffiths, John Richard, Brindle, Kevin Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980847/
https://www.ncbi.nlm.nih.gov/pubmed/27515446
http://dx.doi.org/10.1186/s13550-016-0218-3

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