Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose

Disulfiram is a widely used drug in the management of alcohol dependence syndrome as an aversive agent. Although a drug of high efficacy, it has a large number of side effects. Disulfiram-induced catatonia is a known rare side effect of the drug and herein we report a case of what appeared to be the...

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Autores principales: Kumar, Kiran K., Bondade, Swapna, Sattar, Fiaz Ahmed, Singh, Niharika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980904/
https://www.ncbi.nlm.nih.gov/pubmed/27570348
http://dx.doi.org/10.4103/0253-7176.185944
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author Kumar, Kiran K.
Bondade, Swapna
Sattar, Fiaz Ahmed
Singh, Niharika
author_facet Kumar, Kiran K.
Bondade, Swapna
Sattar, Fiaz Ahmed
Singh, Niharika
author_sort Kumar, Kiran K.
collection PubMed
description Disulfiram is a widely used drug in the management of alcohol dependence syndrome as an aversive agent. Although a drug of high efficacy, it has a large number of side effects. Disulfiram-induced catatonia is a known rare side effect of the drug and herein we report a case of what appeared to be the sequential development of malignant catatonia and neuroleptic malignant syndrome in a patient with a diagnosis of alcohol dependence syndrome and co-morbid paranoid schizophrenia following disulfiram overdose. Clinicians need to be vigilant on the emergence of such rare side effects.
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spelling pubmed-49809042016-08-26 Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose Kumar, Kiran K. Bondade, Swapna Sattar, Fiaz Ahmed Singh, Niharika Indian J Psychol Med Case Report Disulfiram is a widely used drug in the management of alcohol dependence syndrome as an aversive agent. Although a drug of high efficacy, it has a large number of side effects. Disulfiram-induced catatonia is a known rare side effect of the drug and herein we report a case of what appeared to be the sequential development of malignant catatonia and neuroleptic malignant syndrome in a patient with a diagnosis of alcohol dependence syndrome and co-morbid paranoid schizophrenia following disulfiram overdose. Clinicians need to be vigilant on the emergence of such rare side effects. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4980904/ /pubmed/27570348 http://dx.doi.org/10.4103/0253-7176.185944 Text en Copyright: © 2016 Indian Psychiatric Society http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Kumar, Kiran K.
Bondade, Swapna
Sattar, Fiaz Ahmed
Singh, Niharika
Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title_full Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title_fullStr Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title_full_unstemmed Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title_short Malignant Catatonia and Neuroleptic Malignant Syndrome in Relation to Disulfiram Overdose
title_sort malignant catatonia and neuroleptic malignant syndrome in relation to disulfiram overdose
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980904/
https://www.ncbi.nlm.nih.gov/pubmed/27570348
http://dx.doi.org/10.4103/0253-7176.185944
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