Rap1-mediated nuclear factor-kappaB (NF-κB) activity regulates the paracrine capacity of mesenchymal stem cells in heart repair following infarction

Paracrine effect is the major mechanism that underlies mesenchymal stem cells (MSC)-based therapy. This study aimed to examine how Rap1, telomeric repeat-binding factor 2-interacting protein 1 (Terf2IP), which is a novel modulator involved in the nuclear factor-kappaB (NF-κB) pathway, regulates the...

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Detalles Bibliográficos
Autores principales: Zhang, Y, Chiu, S, Liang, X, Gao, F, Zhang, Z, Liao, S, Liang, Y, Chai, Y-H, Low, D J H, Tse, H-F, Tergaonkar, V, Lian, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981000/
https://www.ncbi.nlm.nih.gov/pubmed/27551443
http://dx.doi.org/10.1038/cddiscovery.2015.7

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