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Comparative growth of spotted fever group Rickettsia spp. strains in Vero cells

In Brazil, the spotted fever group (SFG) Rickettsia rickettsii and Rickettsia parkeri related species are the etiological agents of spotted fever rickettsiosis. However, the SFG, Rickettsia rhipicephali, that infects humans, has never been reported. The study of growth dynamics can be useful for und...

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Detalles Bibliográficos
Autores principales: Silva, Arannadia Barbosa, Duarte, Myrian Morato, Vizzoni, Vinicius Figueiredo, Duré, Ana Íris de Lima, Lopéz, Diego Montenegro, Nogueira, Rita de Maria Seabra, Soares, Carlos Augusto Gomes, Machado-Ferreira, Erik, Gazêta, Gilberto Salles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981112/
https://www.ncbi.nlm.nih.gov/pubmed/27508322
http://dx.doi.org/10.1590/0074-02760160093
Descripción
Sumario:In Brazil, the spotted fever group (SFG) Rickettsia rickettsii and Rickettsia parkeri related species are the etiological agents of spotted fever rickettsiosis. However, the SFG, Rickettsia rhipicephali, that infects humans, has never been reported. The study of growth dynamics can be useful for understanding the infective and invasive capacity of these pathogens. Here, the growth rates of the Brazilian isolates R. rickettsii str. Taiaçu, R. parkeri str. At#24, and R. rhipicephali HJ#5, were evaluated in Vero cells by quantitative polymerase chain reaction. R. rhipicephali showed different kinetic growth compared to R. rickettsii and R. parkeri.