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Solubility as a limiting factor for expression of hepatitis A virus proteins in insect cell-baculovirus system
The use of recombinant proteins may represent an alternative model to inactivated vaccines against hepatitis A virus (HAV). The present study aimed to express the VP1 protein of HAV in baculovirus expression vector system (BEVS). The VP1 was expressed intracellularly with molecular mass of 35 kDa. T...
Autores principales: | da Silva, Haroldo Cid, Pestana, Cristiane Pinheiro, Galler, Ricardo, Medeiros, Marco Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Instituto Oswaldo Cruz, Ministério da Saúde
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981117/ https://www.ncbi.nlm.nih.gov/pubmed/27581123 http://dx.doi.org/10.1590/0074-02760160153 |
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