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RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis
In bacterial plasmids, Rep proteins initiate DNA replication by undergoing a structural transformation coupled to dimer dissociation. Amyloidogenesis of the ‘winged-helix’ N-terminal domain of RepA (WH1) is triggered in vitro upon binding to plasmid-specific DNA sequences, and occurs at the bacteria...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981189/ https://www.ncbi.nlm.nih.gov/pubmed/27040981 http://dx.doi.org/10.1080/19336896.2015.1129479 |