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Potential approaches for heterologous prion protein treatment of prion diseases

Prion diseases, or transmissible spongiform encephalopathies (TSEs) are progressive, fatal neurodegenerative diseases with no effective treatment. The pathology of these diseases involves the conversion of a protease sensitive form of the cellular prion protein (PrP(C)) into a protease resistant inf...

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Detalles Bibliográficos
Autores principales: Seelig, Davis M., Goodman, Patricia A., Skinner, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981202/
https://www.ncbi.nlm.nih.gov/pubmed/26636482
http://dx.doi.org/10.1080/19336896.2015.1123372

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