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Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms
Inverted chromosome duplications or palindromes are linked with genetic disorders and malignant transformation. They are considered by-products of DNA double-strand break (DSB) repair: the homologous recombination (HR) and the nonhomologous end joining (NHEJ). Palindromes near chromosome ends are of...
Autores principales: | Raykov, Vasil, Marvin, Marcus E., Louis, Edward J., Maringele, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981268/ https://www.ncbi.nlm.nih.gov/pubmed/27334270 http://dx.doi.org/10.1534/genetics.115.183020 |
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