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Gene, Stem Cell, and Alternative Therapies for SCA 1

Spinocerebellar ataxia 1 is an autosomal dominant disease characterized by neurodegeneration and motor dysfunction. In disease pathogenesis, polyglutamine expansion within Ataxin-1, a gene involved in transcriptional repression, causes protein nuclear inclusions to form. Most notably, neuronal dysfu...

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Detalles Bibliográficos
Autores principales:	Wagner, Jacob L., O'Connor, Deirdre M., Donsante, Anthony, Boulis, Nicholas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981596/ https://www.ncbi.nlm.nih.gov/pubmed/27570504 http://dx.doi.org/10.3389/fnmol.2016.00067

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