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Ablation of STAT3 in the B Cell Compartment Restricts Gammaherpesvirus Latency In Vivo

A challenging property of gammaherpesviruses is their ability to establish lifelong persistence. The establishment of latency in B cells is thought to involve active virus engagement of host signaling pathways. Pathogenic effects of these viruses during latency or following reactivation can be devas...

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Detalles Bibliográficos
Autores principales: Reddy, Sandeep Steven, Foreman, Hui-Chen Chang, Sioux, Thubten Ozula, Park, Gee Ho, Poli, Valeria, Reich, Nancy C., Krug, Laurie T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981709/
https://www.ncbi.nlm.nih.gov/pubmed/27486189
http://dx.doi.org/10.1128/mBio.00723-16

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