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Morphine-Induced Analgesic Tolerance Effect on Gene Expression of the NMDA Receptor Subunit 1 in Rat Striatum and Prefrontal Cortex

INTRODUCTION: Morphine is a potent analgesic but its continual use results in analgesic tolerance. Mechanisms of this tolerance remain to be clarified. However, changes in the functions of μ-opioid and N-Methyl-D-aspartate (NMDA) receptors have been proposed in morphine tolerance. We examined change...

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Detalles Bibliográficos
Autores principales: Ahmadi, Shamseddin, Rafieenia, Fatemeh, Rostamzadeh, Jalal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981836/
https://www.ncbi.nlm.nih.gov/pubmed/27563417
http://dx.doi.org/10.15412/J.BCN.03070309

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