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Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease
Alzheimer’s disease (AD) is one of the most prevalent neurodegenerative diseases, yet current therapeutic treatments are inadequate due to a complex disease pathogenesis. The plant polyphenol apigenin has been shown to have anti-inflammatory and neuroprotective properties in a number of cell and ani...
Autores principales: | Balez, Rachelle, Steiner, Nicole, Engel, Martin, Muñoz, Sonia Sanz, Lum, Jeremy Stephen, Wu, Yizhen, Wang, Dadong, Vallotton, Pascal, Sachdev, Perminder, O’Connor, Michael, Sidhu, Kuldip, Münch, Gerald, Ooi, Lezanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981845/ https://www.ncbi.nlm.nih.gov/pubmed/27514990 http://dx.doi.org/10.1038/srep31450 |
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