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Novel pH-Sensitive Cyclic Peptides
A series of cyclic peptides containing a number of tryptophan (W) and glutamic acid (E) residues were synthesized and evaluated as pH-sensitive agents for targeting of acidic tissue and pH-dependent cytoplasmic delivery of molecules. Biophysical studies revealed the molecular mechanism of peptides a...
Autores principales: | Weerakkody, Dhammika, Moshnikova, Anna, El-Sayed, Naglaa Salem, Adochite, Ramona-Cosmina, Slaybaugh, Gregory, Golijanin, Jovana, Tiwari, Rakesh K., Andreev, Oleg A., Parang, Keykavous, Reshetnyak, Yana K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981864/ https://www.ncbi.nlm.nih.gov/pubmed/27515582 http://dx.doi.org/10.1038/srep31322 |
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