HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR

The members of the epidermal growth factor receptor (EGFR) kinase family are important players in breast morphogenesis and cancer. EGFR2/HER2 and EGFR expression have a prognostic value in certain subtypes of breast cancer such as HER2-amplified, basal-like and luminal type B. Many clinically approv...

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Detalles Bibliográficos
Autores principales: Ingthorsson, S, Andersen, K, Hilmarsdottir, B, Maelandsmo, G M, Magnusson, M K, Gudjonsson, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981873/
https://www.ncbi.nlm.nih.gov/pubmed/26686087
http://dx.doi.org/10.1038/onc.2015.489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981873/
https://www.ncbi.nlm.nih.gov/pubmed/26686087
http://dx.doi.org/10.1038/onc.2015.489

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