Cargando…
HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR
The members of the epidermal growth factor receptor (EGFR) kinase family are important players in breast morphogenesis and cancer. EGFR2/HER2 and EGFR expression have a prognostic value in certain subtypes of breast cancer such as HER2-amplified, basal-like and luminal type B. Many clinically approv...
Autores principales: | Ingthorsson, S, Andersen, K, Hilmarsdottir, B, Maelandsmo, G M, Magnusson, M K, Gudjonsson, T |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981873/ https://www.ncbi.nlm.nih.gov/pubmed/26686087 http://dx.doi.org/10.1038/onc.2015.489 |
Ejemplares similares
-
Inhibition of PTP1B disrupts cell–cell adhesion and induces anoikis in breast epithelial cells
por: Hilmarsdottir, Bylgja, et al.
Publicado: (2017) -
Context-Dependent Function of Myoepithelial Cells in Breast Morphogenesis and Neoplasia
por: Ingthorsson, Saevar, et al.
Publicado: (2015) -
Endothelial Induced EMT in Breast Epithelial Cells with Stem Cell Properties
por: Sigurdsson, Valgardur, et al.
Publicado: (2011) -
Expression and Functional Role of Sprouty-2 in Breast Morphogenesis
por: Sigurdsson, Valgardur, et al.
Publicado: (2013) -
EMT-Induced Stemness and Tumorigenicity Are Fueled by the EGFR/Ras Pathway
por: Voon, Dominic Chih-Cheng, et al.
Publicado: (2013)