Oncogenic CARMA1 couples NF-κB and β-catenin signaling in diffuse large B-cell lymphomas

Constitutive activation of the antiapoptotic nuclear factor-κB (NF-κB) signaling pathway is a hallmark of the activated B-cell-like (ABC) subtype of diffuse large B-cell lymphomas (DLBCL). Recurrent oncogenic mutations are found in the scaffold protein CARMA1 (CARD11) that connects B-cell receptor (...

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Detalles Bibliográficos
Autores principales: Bognar, M K, Vincendeau, M, Erdmann, T, Seeholzer, T, Grau, M, Linnemann, J R, Ruland, J, Scheel, C H, Lenz, P, Ott, G, Lenz, G, Hauck, S M, Krappmann, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981874/
https://www.ncbi.nlm.nih.gov/pubmed/26776161
http://dx.doi.org/10.1038/onc.2015.493

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