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A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles
Survivin, the smallest member of the inhibitor of apoptosis protein family, plays a central role during mitosis and exerts a cytoprotective function. Survivin is highly expressed in most cancer types and contributes to multiple facets of carcinogenesis. The molecular mechanisms underlying its highly...
Autores principales: | Beghein, Els, Van Audenhove, Isabel, Zwaenepoel, Olivier, Verhelle, Adriaan, De Ganck, Ariane, Gettemans, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981888/ https://www.ncbi.nlm.nih.gov/pubmed/27514728 http://dx.doi.org/10.1038/srep31177 |
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