Cargando…

Evaluating the effectiveness of transferrin receptor‐1 (TfR1) as a magnetic resonance reporter gene

Magnetic resonance (MR) reporter genes have the potential for tracking the biodistribution and fate of cells in vivo, thus allowing the safety, efficacy and mechanisms of action of cell‐based therapies to be comprehensively assessed. In this study, we evaluate the effectiveness of the iron importer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pereira, Sofia M., Herrmann, Anne, Moss, Diana, Poptani, Harish, Williams, Steve R., Murray, Patricia, Taylor, Arthur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981909/ https://www.ncbi.nlm.nih.gov/pubmed/26929139 http://dx.doi.org/10.1002/cmmi.1686

Ejemplares similares

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants
por: Bien-Ly, Nga, et al.
Publicado: (2014)

Antibodies Targeting the Transferrin Receptor 1 (TfR1) as Direct Anti-cancer Agents
por: Candelaria, Pierre V., et al.
Publicado: (2021)

Identification and Characterization of Elevated Expression of Transferrin and Its Receptor TfR1 in Mouse Models of Depression
por: Chang, Xin, et al.
Publicado: (2022)

Structure prediction of transferrin receptor protein 1 (TfR1) by homology modelling, docking, and molecular dynamics simulation studies
por: AL-Refaei, Maha Ateeq, et al.
Publicado: (2020)

Age, dose, and binding to TfR on blood cells influence brain delivery of a TfR-transported antibody
por: Faresjö, Rebecca, et al.
Publicado: (2023)

Regulation of mitochondrial morphology and function by Stearoylation of TfR1
por: Senyilmaz, Deniz, et al.
Publicado: (2015)

Expression of transferrin receptor‐1 (TFR‐1) in canine osteosarcomas
por: De Vico, Gionata, et al.
Publicado: (2020)

Rational design of universal immunotherapy for TfR1-tropic arenaviruses
por: Cohen-Dvashi, Hadas, et al.
Publicado: (2020)

Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases
por: Herrmann, Anne, et al.
Publicado: (2018)

TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
por: Kenneth, Niall S., et al.
Publicado: (2012)

Downregulation of TfR1 promotes progression of colorectal cancer via the JAK/STAT pathway
por: Cui, Can, et al.
Publicado: (2019)

Machine Learning Classifies Ferroptosis and Apoptosis Cell Death Modalities with TfR1 Immunostaining
por: Jin, Jenny, et al.
Publicado: (2022)

Overexpression of the MRI Reporter Genes Ferritin and Transferrin Receptor Affect Iron Homeostasis and Produce Limited Contrast in Mesenchymal Stem Cells
por: Pereira, Sofia M., et al.
Publicado: (2015)

Identification of a Novel Inhibitor of TfR1 from Designed and Synthesized Muriceidine A Derivatives
por: Wu, Yu, et al.
Publicado: (2022)

CDR3 Variants of the TXB2 Shuttle with Increased TfR1 Association Rate and Enhanced Brain Penetration
por: Stocki, Pawel, et al.
Publicado: (2023)

Efficacy of Antibodies Targeting TfR1 in Xenograft Mouse Models of AIDS-Related Non-Hodgkin Lymphoma
por: Daniels-Wells, Tracy R., et al.
Publicado: (2023)

Anaplastic Thyroid Carcinoma: Current Treatments and Potential New Therapeutic Options with Emphasis on TfR1/CD71
por: Parenti, Rosalba, et al.
Publicado: (2014)

Integrated analysis identifies TfR1 as a prognostic biomarker which correlates with immune infiltration in breast cancer
por: Chen, Fei, et al.
Publicado: (2021)

Lipid vesicles containing transferrin receptor binding peptide TfR-T(12) and octa-arginine conjugate stearyl-R(8) efficiently treat brain glioma along with glioma stem cells
por: Mu, Li-Min, et al.
Publicado: (2017)

Expanding virus susceptibility spectrum of MDBK cells by expressing host receptors nectin 4 and TfR
por: Han, Peiyu, et al.
Publicado: (2021)

Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma
por: Spellerberg, Rebekka, et al.
Publicado: (2022)

Evaluation of ferritin and TfR level in plasma neural-derived exosomes as potential markers of Parkinson’s disease
por: Chen, Zhi-ting, et al.
Publicado: (2023)

TfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer
por: Cheng, Xiaojing, et al.
Publicado: (2020)

Magnetospirillum magneticum as a Living Iron Chelator Induces TfR1 Upregulation and Decreases Cell Viability in Cancer Cells
por: Menghini, Stefano, et al.
Publicado: (2021)

Identification of Transferrin Receptor 1 (TfR1) Overexpressed in Lung Cancer Cells, and Internalization of Magnetic Au-CoFe(2)O(4) Core-Shell Nanoparticles Functionalized with Its Ligand in a Cellular Model of Small Cell Lung Cancer (SCLC)
por: Villalobos-Manzo, Rocío, et al.
Publicado: (2022)

Dual single-scission event analysis of constitutive transferrin receptor (TfR) endocytosis and ligand-triggered β2-adrenergic receptor (β2AR) or Mu-opioid receptor (MOR) endocytosis
por: Lampe, Marko, et al.
Publicado: (2014)

Blood TfR+ exosomes separated by a pH-responsive method deliver chemotherapeutics for tumor therapy
por: Yang, Lijun, et al.
Publicado: (2019)

Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication
por: Mehta, Kosha J., et al.
Publicado: (2020)

Correction: TfR1 binding with H-ferritin nanocarrier achieves prognostic diagnosis and enhances the therapeutic efficacy in clinical gastric cancer
por: Cheng, Xiaojing, et al.
Publicado: (2022)

Salvia miltiorrhiza (SM) Injection Ameliorates Iron Overload-Associated Cardiac Dysfunction by Regulating the Expression of DMT1, TfR1, and FP1 in Rats
por: Zhang, Yuanyuan, et al.
Publicado: (2021)

Blood TfR+ exosomes separated by a pH-responsive method deliver chemotherapeutics for tumor therapy: Erratum
por: Yang, Lijun, et al.
Publicado: (2021)

Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice
por: Desjardins, Cody A, et al.
Publicado: (2022)

Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage
por: DeGregorio-Rocasolano, Nuria, et al.
Publicado: (2017)

Measurement of serum transferrin receptor (sTfR) in critically ill patients
por: Kolias, S, et al.
Publicado: (2001)

In Situ Proximity Ligation Assays Indicate That Hemochromatosis Proteins Hfe and Transferrin Receptor 2 (Tfr2) Do Not Interact
por: Rishi, Gautam, et al.
Publicado: (2013)

Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death
por: Sanguigno, Luca, et al.
Publicado: (2023)

Structural rearrangement of Neisseria meningitidis transferrin binding protein A (TbpA) prior to human transferrin protein (hTf) binding
por: DURAN, Gizem Nur, et al.
Publicado: (2021)

Magnetic Resonance Spectroscopy for Detection of 2-Hydroxyglutarate as a Biomarker for IDH Mutation in Gliomas
por: Leather, Thomas, et al.
Publicado: (2017)

Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion‐independent a murine model of transfusion‐dependent β‐thalassemia
por: Di Modica, Simona Maria, et al.
Publicado: (2022)

Assessing the Efficacy of Nano- and Micro-Sized Magnetic Particles as Contrast Agents for MRI Cell Tracking
por: Taylor, Arthur, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_tv11jhdhtb787a703npe3klamv