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Transient Canonical Wnt Stimulation Enriches Human Bone Marrow Mononuclear Cell Isolates for Osteoprogenitors

Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. Emerging data suggest that activation of the Wnt signaling pathway promotes bone mineral accrual in osteoporotic patients. The effect of Wnt stimulation in fracture healing is less clear as Wnt...

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Detalles Bibliográficos
Autores principales: Janeczek, Agnieszka A., Tare, Rahul S., Scarpa, Edoardo, Moreno‐Jimenez, Ines, Rowland, Caroline A., Jenner, Dominic, Newman, Tracey A., Oreffo, Richard O. C., Evans, Nicholas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981914/
https://www.ncbi.nlm.nih.gov/pubmed/26573091
http://dx.doi.org/10.1002/stem.2241