‘2A‐Like’ Signal Sequences Mediating Translational Recoding: A Novel Form of Dual Protein Targeting

We report the initial characterization of an N‐terminal oligopeptide ‘2A‐like’ sequence that is able to function both as a signal sequence and as a translational recoding element. Owing to this translational recoding activity, two forms of nascent polypeptide are synthesized: (i) when 2A‐mediated tr...

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Detalles Bibliográficos
Autores principales: Roulston, Claire, Luke, Garry A., de Felipe, Pablo, Ruan, Lin, Cope, Jonathan, Nicholson, John, Sukhodub, Andriy, Tilsner, Jens, Ryan, Martin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981915/
https://www.ncbi.nlm.nih.gov/pubmed/27161495
http://dx.doi.org/10.1111/tra.12411

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