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Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs

BACKGROUND: rDNA, the genes encoding ribosomal RNA (rRNA), is highly demanded for ribosome production and protein synthesis in growing cells such as pluripotent stem cells. rDNA transcription activity varies between cell types, metabolism conditions, and specific environmental challenges. Embryonic...

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Detalles Bibliográficos
Autores principales:	Zhao, Qiaoshi, Wu, Yanshuang, Shan, Zhiyan, Bai, Guangyu, Wang, Zhendong, Hu, Jing, Liu, Li, Li, Tong, Shen, Jingling, Lei, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981958/ https://www.ncbi.nlm.nih.gov/pubmed/27515169 http://dx.doi.org/10.1186/s13287-016-0369-1

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