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Cascade Metathesis Reactions for the Synthesis of Taxane and Isotaxane Derivatives

Tricyclic isotaxane and taxane derivatives have been synthesized by a very efficient cascade ring‐closing dienyne metathesis (RCDEYM) reaction, which formed the A and B rings in one operation. When the alkyne is present at C13 (with no neighboring gem‐dimethyl group), the RCEDYM reaction leads to 14...

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Detalles Bibliográficos
Autores principales: Ma, Cong, Letort, Aurélien, Aouzal, Rémi, Wilkes, Antonia, Maiti, Gourhari, Farrugia, Louis J., Ricard, Louis, Prunet, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982030/
https://www.ncbi.nlm.nih.gov/pubmed/27062670
http://dx.doi.org/10.1002/chem.201600592

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