Interleukin‐6 receptor alpha blockade improves skin lesions in a murine model of systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune disease, characterized by antinuclear autoantibodies (ANA) and immunocomplexes, commonly affecting kidneys, skin, heart, lung or even the brain. We have shown that JunB(Δep) mice develop a SLE phenotype linked to increased epidermal Interleukin (IL...

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Detalles Bibliográficos
Autores principales: Birner, Peter, Heider, Susanne, Petzelbauer, Peter, Wolf, Peter, Kornauth, Christoph, Kuroll, Madeleine, Merkel, Olaf, Steiner, Günter, Kishimoto, Tadamitsu, Rose‐John, Stefan, Soleiman, Afschin, Moriggl, Richard, Kenner, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982049/
https://www.ncbi.nlm.nih.gov/pubmed/26739431
http://dx.doi.org/10.1111/exd.12934

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