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Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis

Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9‐membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a nonadride) and agnestadride A (a heptadride) was investigated through gene disruptio...

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Detalles Bibliográficos
Autores principales:	Williams, Katherine, Szwalbe, Agnieszka J., Mulholland, Nicholas P., Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Simpson, Thomas J., Cox, Russell J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982102/ https://www.ncbi.nlm.nih.gov/pubmed/27099957 http://dx.doi.org/10.1002/anie.201511882

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