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The catalytic power of magnesium chelatase: a benchmark for the AAA (+) ATPases
In the first committed reaction of chlorophyll biosynthesis, magnesium chelatase couples ATP hydrolysis to the thermodynamically unfavorable Mg(2+) insertion into protoporphyrin IX (ΔG°′ of circa 25–33 kJ·mol(−1)). We explored the thermodynamic constraints on magnesium chelatase and demonstrate the...
Autores principales: | Adams, Nathan B. P., Brindley, Amanda A., Hunter, C. Neil, Reid, James D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982103/ https://www.ncbi.nlm.nih.gov/pubmed/27176620 http://dx.doi.org/10.1002/1873-3468.12214 |
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