Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling

BACKGROUND: In HIV-1 infected cells, the integrated viral DNA is transcribed by the host cell machinery to generate the full length HIV-1 RNA (FL RNA) that serves as mRNA encoding for the Gag and GagPol precursors. Virion formation is orchestrated by Gag, and the current view is that a specific inte...

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Detalles Bibliográficos
Autores principales: Mekdad, Hala El, Boutant, Emmanuel, Karnib, Hassan, Biedma, Marina E., Sharma, Kamal Kant, Malytska, Iuliia, Laumond, Géraldine, Roy, Marion, Réal, Eléonore, Paillart, Jean-Christophe, Moog, Christiane, Darlix, Jean Luc, Mély, Yves, de Rocquigny, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982112/
https://www.ncbi.nlm.nih.gov/pubmed/27515235
http://dx.doi.org/10.1186/s12977-016-0287-4

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