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shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury

BACKGROUND: Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn injury, and the hypothesis that knockdown of Nav1.7 attenuates pain following...

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Detalles Bibliográficos
Autores principales: Cai, Weihua, Cao, Jing, Ren, Xiuhua, Qiao, Liang, Chen, Xuemei, Li, Ming, Zang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982321/
https://www.ncbi.nlm.nih.gov/pubmed/27514860
http://dx.doi.org/10.1186/s12871-016-0215-0

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