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shRNA mediated knockdown of Nav1.7 in rat dorsal root ganglion attenuates pain following burn injury
BACKGROUND: Abnormal acute pain after burn injury still torments patients severely. In this study, we investigated that one voltage gated sodium channel Nav1.7 plays a vital role in lowering heat pain threshold after burn injury, and the hypothesis that knockdown of Nav1.7 attenuates pain following...
Autores principales: | Cai, Weihua, Cao, Jing, Ren, Xiuhua, Qiao, Liang, Chen, Xuemei, Li, Ming, Zang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982321/ https://www.ncbi.nlm.nih.gov/pubmed/27514860 http://dx.doi.org/10.1186/s12871-016-0215-0 |
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