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Development and validation of an Onchocerca ochengi microfilarial hamster model for onchocerciasis drug screens
BACKGROUND: Onchocerciasis, caused by the parasitic nematode, Onchocerca volvulus afflicts some 37 million people worldwide, and is the second leading infectious cause of blindness globally. The only currently recommended drug for treatment of the disease, ivermectin, is only microfilaricidal and ha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982420/ https://www.ncbi.nlm.nih.gov/pubmed/27515037 http://dx.doi.org/10.1186/s12879-016-1753-2 |