Optical coherence tomography findings of bilateral foveal leukemic infiltration

We report a case of a 59-year-old man with a history of atypical chronic myelogenous leukemia who presented with a several-week history of decreased vision in both eyes. His clinical examination revealed bilateral foveal infiltration, which was also demonstrated on optical coherence tomography. Afte...

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Autores principales: Le, John Q, Braich, Puneet S, Brar, Vikram S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982485/
https://www.ncbi.nlm.nih.gov/pubmed/27540313
http://dx.doi.org/10.2147/IMCRJ.S103723
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author Le, John Q
Braich, Puneet S
Brar, Vikram S
author_facet Le, John Q
Braich, Puneet S
Brar, Vikram S
author_sort Le, John Q
collection PubMed
description We report a case of a 59-year-old man with a history of atypical chronic myelogenous leukemia who presented with a several-week history of decreased vision in both eyes. His clinical examination revealed bilateral foveal infiltration, which was also demonstrated on optical coherence tomography. After a failed induction with imatinib (Gleevec(®)), he was treated with omacetaxine (Synribo(®)) with an appropriate hematologic response. As his leukemia improved with chemotherapy, his retinal lesions regressed as demonstrated by serial optical coherence tomography and fundus photographs, with near complete restoration of foveal architecture.
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spelling pubmed-49824852016-08-18 Optical coherence tomography findings of bilateral foveal leukemic infiltration Le, John Q Braich, Puneet S Brar, Vikram S Int Med Case Rep J Case Report We report a case of a 59-year-old man with a history of atypical chronic myelogenous leukemia who presented with a several-week history of decreased vision in both eyes. His clinical examination revealed bilateral foveal infiltration, which was also demonstrated on optical coherence tomography. After a failed induction with imatinib (Gleevec(®)), he was treated with omacetaxine (Synribo(®)) with an appropriate hematologic response. As his leukemia improved with chemotherapy, his retinal lesions regressed as demonstrated by serial optical coherence tomography and fundus photographs, with near complete restoration of foveal architecture. Dove Medical Press 2016-08-08 /pmc/articles/PMC4982485/ /pubmed/27540313 http://dx.doi.org/10.2147/IMCRJ.S103723 Text en © 2016 Le et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Le, John Q
Braich, Puneet S
Brar, Vikram S
Optical coherence tomography findings of bilateral foveal leukemic infiltration
title Optical coherence tomography findings of bilateral foveal leukemic infiltration
title_full Optical coherence tomography findings of bilateral foveal leukemic infiltration
title_fullStr Optical coherence tomography findings of bilateral foveal leukemic infiltration
title_full_unstemmed Optical coherence tomography findings of bilateral foveal leukemic infiltration
title_short Optical coherence tomography findings of bilateral foveal leukemic infiltration
title_sort optical coherence tomography findings of bilateral foveal leukemic infiltration
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982485/
https://www.ncbi.nlm.nih.gov/pubmed/27540313
http://dx.doi.org/10.2147/IMCRJ.S103723
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