Tumor-reactive immune cells protect against metastatic tumor and induce immunoediting of indolent but not quiescent tumor cells

Two major barriers to cancer immunotherapy include tumor-induced immune suppression mediated by myeloid-derived suppressor cells and poor immunogenicity of the tumor-expressing self-antigens. To overcome these barriers, we reprogrammed tumor-immune cell cross-talk by combined use of decitabine and a...

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Detalles Bibliográficos
Autores principales: Payne, Kyle K., Keim, Rebecca C., Graham, Laura, Idowu, Michael O., Wan, Wen, Wang, Xiang-Yang, Toor, Amir A., Bear, Harry D., Manjili, Masoud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Leukocyte Biology 2016
Materias:
Translational & Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982610/
https://www.ncbi.nlm.nih.gov/pubmed/26928306
http://dx.doi.org/10.1189/jlb.5A1215-580R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982610/
https://www.ncbi.nlm.nih.gov/pubmed/26928306
http://dx.doi.org/10.1189/jlb.5A1215-580R

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