Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F(1)F(o)-ATPase

BACKGROUND: Isometamidium is the main prophylactic drug used to prevent the infection of livestock with trypanosomes that cause Animal African Trypanosomiasis. As well as the animal infective trypanosome species, livestock can also harbor the closely related human infective subspecies T. b. gambiens...

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Detalles Bibliográficos
Autores principales: Eze, Anthonius A., Gould, Matthew K., Munday, Jane C., Tagoe, Daniel N. A., Stelmanis, Valters, Schnaufer, Achim, De Koning, Harry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982688/
https://www.ncbi.nlm.nih.gov/pubmed/27518185
http://dx.doi.org/10.1371/journal.pntd.0004791

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