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MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network

MiR-34a was demonstrated to be upregulated during the osteogenic differentiation of human adipose-derived stem cells (hASCs). Overexpression of miR-34a significantly increased alkaline phosphatase activity, mineralization capacity, and the expression of osteogenesis-associated genes in hASCs in vitr...

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Detalles Bibliográficos
Autores principales: Fan, Cong, Jia, Lingfei, Zheng, Yunfei, Jin, Chanyuan, Liu, Yunsong, Liu, Hao, Zhou, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982986/
https://www.ncbi.nlm.nih.gov/pubmed/27453008
http://dx.doi.org/10.1016/j.stemcr.2016.06.010