H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro

Although pluripotent stem cells can be differentiated into the hepatocyte lineages, such cells retain an immature phenotype. As the chromatin state of regulatory regions controls spatiotemporal gene expression during development, we evaluated changes in epigenetic histone marks in lineage-specific g...

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Detalles Bibliográficos
Autores principales: Vanhove, Jolien, Pistoni, Mariaelena, Welters, Marc, Eggermont, Kristel, Vanslembrouck, Veerle, Helsen, Nicky, Boon, Ruben, Najimi, Mustapha, Sokal, Etienne, Collas, Philippe, Voncken, J. Willem, Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982990/
https://www.ncbi.nlm.nih.gov/pubmed/27477635
http://dx.doi.org/10.1016/j.stemcr.2016.06.013

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