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The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles
The innate immune system is the first line of defense against inhaled particles. Macrophages serve important roles in particle clearance and inflammatory reactions. Following recognition and internalization by phagocytes, particles are taken up in vesicular phagolysosomes. Intracellular phagosomal l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983011/ https://www.ncbi.nlm.nih.gov/pubmed/27519871 http://dx.doi.org/10.1186/s12989-016-0150-8 |