Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?

Multiple sclerosis (MS) is associated with breakdown of the myelin sheath that coats neurons in the central nervous system. The cause of MS is not known, although the pathogenesis involves destruction of myelin by the immune system. It was the aim of this study to examine the abundant myelin protein...

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Detalles Bibliográficos
Autores principales: Friedrich, Michael G., Hancock, Sarah E., Raftery, Mark J., Truscott, Roger J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983062/
https://www.ncbi.nlm.nih.gov/pubmed/27519525
http://dx.doi.org/10.1186/s40478-016-0348-x

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