Role of KIR and CD16A genotypes in colorectal carcinoma genetic risk and clinical stage

BACKGROUND: NK cell cytotoxicity is regulated by the types of the interaction between killer immunoglobulin-like receptors (KIRs) and human leukocyte antigen (HLA) class I ligands on target cells and the different binding affinity of the Fcγ receptor IIIA (CD16A) for IgG-coated tumor cells. Thus, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Canossi, Angelica, Aureli, Anna, Del Beato, Tiziana, Rossi, Piero, Franceschilli, Luana, De Sanctis, Flavio, Sileri, Pierpaolo, di Lorenzo, Nicola, Buonomo, Oreste, Lauro, Davide, Venditti, Adriano, Sconocchia, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983069/
https://www.ncbi.nlm.nih.gov/pubmed/27519478
http://dx.doi.org/10.1186/s12967-016-1001-y

Ejemplares similares

Ejemplares similares