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Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency

Embryonic stem cells (ESCs) are cell lines derived from the mammalian pre-implantation embryo. Here we assess the impact of derivation and culture conditions on both functional potency and ESC transcriptional identity. Individual ESCs cultured in either two small-molecule inhibitors (2i) or with kno...

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Detalles Bibliográficos
Autores principales:	Martin Gonzalez, Javier, Morgani, Sophie M., Bone, Robert A., Bonderup, Kasper, Abelchian, Sahar, Brakebusch, Cord, Brickman, Joshua M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983099/ https://www.ncbi.nlm.nih.gov/pubmed/27509134 http://dx.doi.org/10.1016/j.stemcr.2016.07.009

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