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Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in newborn macaques
Prevention of mother to child transmission (MTCT) of HIV remains a major objective where antenatal care is not readily accessible. We tested anti-HIV-1 human neutralizing monoclonal antibodies (NmAb) as post-exposure therapy in an infant macaque model for intrapartum MTCT. One-month-old rhesus macaq...
Autores principales: | Hessell, Ann J., Jaworski, J. Pablo, Epson, Erin, Matsuda, Kenta, Pandey, Shilpi, Kahl, Christoph, Reed, Jason, Sutton, William F., Hammond, Katherine B., Cheever, Tracy A., Barnette, Philip T., Legasse, Alfred W., Planer, Shannon, Stanton, Jeffrey J., Pegu, Amarendra, Chen, Xuejun, Wang, Keyun, Siess, Don, Burke, David, Park, Byung S., Axthelm, Michael K., Lewis, Anne, Hirsch, Vanessa M., Graham, Barney S., Mascola, John R., Sacha, Jonah B., Haigwood, Nancy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983100/ https://www.ncbi.nlm.nih.gov/pubmed/26998834 http://dx.doi.org/10.1038/nm.4063 |
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