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Omeprazole impairs vascular redox biology and causes xanthine oxidoreductase-mediated endothelial dysfunction
Proton pump inhibitors (PPIs) are widely used drugs that may increase the cardiovascular risk by mechanisms not entirely known. While PPIs increase asymmetric dimethylarginine (ADMA) levels and inhibit nitric oxide production, it is unknown whether impaired vascular redox biology resulting of increa...
Autores principales: | Pinheiro, Lucas C., Oliveira-Paula, Gustavo H., Portella, Rafael L., Guimarães, Danielle A., de Angelis, Celio D., Tanus-Santos, Jose E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983109/ https://www.ncbi.nlm.nih.gov/pubmed/27521759 http://dx.doi.org/10.1016/j.redox.2016.08.001 |
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