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Emerging Technologies and Generic Assays for the Detection of Anti-Drug Antibodies

Anti-drug antibodies induced by biologic therapeutics often impact drug pharmacokinetics, pharmacodynamics response, clinical efficacy, and patient safety. It is critical to assess the immunogenicity risk of potential biotherapeutics in producing neutralizing and nonneutralizing anti-drug antibodies...

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Detalles Bibliográficos
Autores principales: Partridge, Michael A., Purushothama, Shobha, Elango, Chinnasamy, Lu, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983396/
https://www.ncbi.nlm.nih.gov/pubmed/27556048
http://dx.doi.org/10.1155/2016/6262383